Biogenic synthesis of selenium nanoparticles using Hibiscus esculentus L. extract: Catalytic degradation of organic dye and its anticancer, antibacterial and antifungal activities

In this work, we develop the synthesis of selenium nanoparticles (B@SeNPs) using a green method aqueous extract Hibiscus esculentus L. Various techniques were used to characterize bio-synthesized B@SeNPs. The mixture color was clearly changed reddish at 45-50 °C and pH = 6. According Fourier transform infrared spectroscopy (FT-IR), B@SeNPs produced, capped, stabilized biomolecules found in plant extracts. energy dispersive X-ray (EDX) analysis profile revealed an atomic Se signal (1.39 mV). powder diffraction (PXRD) pattern confirmed hexagonal phase crystalline form zeta potential for SeNPs determined be -51.3 mV. Scanning electron microscope (SEM) transmission microscopy (TEM) micrographs spherical particles with sizes roughly 62 nm. Furthermore, can degrade methylene blue dye by 98.3% 21 min rate constant 0.1023 min-1 presence NaBH4. biological evaluation, synthesized have been proven effective against two human cancers (AGS MCF-7 cells) IC50 values 20.46 88.43 µg/mL, respectively. Additionally, showed high safety Beas cell line (normal) 123 µg/mL as highest concentration. biofabricated had moderate antibacterial effect ATCC multidrug-resistant clinical isolates. They no antifungal activity tested fungus strains except C. albicans (IFRC 1873), MIC value 138.75 µg/mL. Finally, green-synthesized could contender further testing chemotherapeutic agent treatment some cancers.